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Vitamin D supports immune function, bone health and overall well-being. Emerging Research continues to explore its influence on maintaining a healthy lifestyle. Fermenta, a leading manufacturer of Vitamin D, presents this D-Essence Newsletter to highlight the latest research on Vitamin D and its role in maintaining overall health.
Vitamin D supplementation possibly improves glycemic control in T2D
Emerging research is uncovering the potential of Vitamin D in supporting healthy glucose metabolism and cardiovascular function. A systematic review and meta-analysis have underscored the importance of maintaining adequate Vitamin D levels for overall well-being. Vitamin D supplementation lowered the HbA1c, fasting blood glucose, SBP and low-density lipoprotein levels by the standard mean difference (SMD) of -0.15, -0.28, -0.06 and -0.11, respectively. Similarly, the average high-density lipoprotein and Vitamin D levels increased by 0.13 SMD and 1.78 IU with Vitamin D supplementation, respectively. Factors such as body weight and the duration of certain health conditions may influence responses to supplementation.
Afraie M et al. J Diabetes Res. 2024 Sep 10;2024:9960656
Vitamin D supplementation probably mitigates exacerbation risk in COPD
The relationship between Vitamin D supplementation and 100 COPD patients explores the potential role of Vitamin D in maintaining healthy lung function. A prospective study examined the relationship between Vitamin D levels and respiratory well-being in 100 individuals with COPD. The majority of participants (96%) were found to have low Vitamin D levels, which improved following three months of supplementation, increasing from an average of 14.71 nmol/L to 45.56 nmol/L. Supplementation was also associated with improvements in overall respiratory health, as indicated by a decrease of 4.2 points in the COPD assessment Test (CAT) score, compared to a 1.4 point increase in the group not receiving supplementation. Additionally, participants receiving Vitamin D reported fewer respiratory issues over a year, along with a reduction in emergency visits.
Lakra A et al. Monaldi Arch Chest Dis. 2024 Mar 1
Vitamin D levels may influence health outcomes in heart health
A prospective study of 5,452 individuals with coronary heart conditions explored the potential relationship between Vitamin D status, inflammation and the body’s natural regenerative processes. Approximately 44% of the participants had Vitamin D levels <20 ng/mL. These individuals demonstrated a 60%, 57% and 54% higher likelihood of experiencing all-cause death, CV death and MACE, respectively, than those with sufficient Vitamin D levels. Participants with low Vitamin D levels also showed 45% higher levels of hsCRP, an indicator of inflammation, compared with normal (>30 ng/mL) levels. Both low Vitamin D levels and reduced counts of circulating progenitor cells (CPCs), which is linked to the body’s regenerative capacity, demonstrated a 2.25 fold higher likelihood of CV mortality compared to those with adequate Vitamin D and CPC levels.
Desai SR et al. JACC Adv. 2024 Jan 4;3(2):100804
Disclaimer: The contents of this scientific issue have been developed by FourC Healthvistas Pvt. Ltd. for Fermenta Biotech Ltd., from reasonable and reliable information published in literature as cited. This is for information purpose only and not a substitute to medical advice. Although great care has been taken in compiling and checking the information, the authors, FourC Healthvistas Pvt. Ltd., Fermenta Biotech Ltd., its employees and/or its agents & sponsors shall not be responsible, or in anyway liable for any errors, omissions or inaccuracies in this publication, whether arising from negligence or otherwise, or for any consequences arising therefrom.
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