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As Vitamin D is essential for various immune responses and metabolic pathways, maintaining adequate levels is crucial. Supplementing with Vitamin D can support overall wellness, including promoting healthy bone and muscle function, and supporting immune health. Fermenta, a leading manufacturer of Vitamin D, presents this D-Essence Newsletter to highlight the latest research on Vitamin D and its role in maintaining overall health. |
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Vitamin D supports treatment course in extrapulmonary TB patients
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A study analyzed the impact of combining Vitamin D supplementation to anti-TB therapy on extrapulmonary TB (EPTB) patients. Overall, Vitamin D deficiency (<30 nmol/L) was found in 100% of the patients with EPTB. At 12 months, Vitamin D supplementation was associated with a 2 kg and 1.2 g/dl greater increase in weight and hemoglobin level from baseline, respectively, Vs. without supplementation. The liver biochemical profile and inflammatory marker levels also improved with Vitamin D supplementation. Among TB pleurisy cases, Vitamin D supplementation showed a 100% resolution rate of pleural fluid at 6 months.
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| Eletreby R et al. BMC Infect Dis. 2024 Jul 9;24(1):681 |
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Vitamin D supports healthy metabolic function in PCOS
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A randomized controlled trial examined the effect of Vitamin D supplementation on metabolic parameters among 60 women with PCOS. After 12 weeks, Vitamin D supplementation resulted in a 31 ng/ml greater increase in serum Vitamin D level from baseline compared to control group. Additionally, there was a 7- and 2-fold greater improvement in body mass index and waist to hip ratio with Vitamin D supplementation, respectively, Vs. control. Furthermore, Vitamin D supplementation reduced the serum insulin concentration, insulin resistance and improved the lipid profile in PCOS women, especially in those with obesity Vs. control.
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| Wen X et al. J Ovarian Res. 2024 Jul 16;17(1):147 |
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Vitamin D supports muscle health & muscle function in chronic liver disease patients
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A retrospective study evaluated the association between Vitamin D level and muscle mass loss in patients with chronic liver disease. Among 166 patients, those with muscle mass loss had a Vitamin D level of 12.5 ng/mL Vs. 16.2 ng/mL in those without muscle mass loss at baseline. Multivariate analysis revealed low Vitamin D level as an independent factor correlated with muscle mass loss. Compared to Vitamin D level of ≥12.7 ng/mL, the incidence of muscle mass loss was 3-fold higher among patients with <12.7 ng/mL of Vitamin D level; with highest incidence found in non-alcoholic fatty liver disease patients.
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| Okubo T et al. PLoS One. 2024 Mar 26;19(3):e0299313
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Disclaimer: The contents of this scientific issue have been developed by FourC Healthvistas Pvt. Ltd. for Fermenta Biotech Ltd., from reasonable and reliable information published in literature as cited. This is for information purpose only and not a substitute to medical advice. Although great care has been taken in compiling and checking the information, the authors, FourC Healthvistas Pvt. Ltd., Fermenta Biotech Ltd., its employees and/or its agents & sponsors shall not be responsible, or in anyway liable for any errors, omissions or inaccuracies in this publication, whether arising from negligence or otherwise, or for any consequences arising therefrom.
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