Granted patents

• Czech patent 300467: “DNA sequence encoding Penicillin Acylase, Novel Recombinant DNA constructs and Recombinant Microorganisms carrying this sequence”, granted on 21.4.2009. 

• European patent 2173892 B8 “Process for the preparation of Immobilized recombinant Penicillin Acylase Catalyst from Achromobacter SP. CCM 4824 expressed in E. COLI BL 21 CCM 7394 and its use for the synthesis of Beta Lactam Antibiotics”, granted on 21.9.2011. Find it on Google Patents Search

• US patent 8039604B2: “DNA sequence encoding Penicillin Acylase, Novel Recombinant DNA constructs and Recombinant Microorganisms carrying this sequence”, granted on 18.10.2011. Find it on Google Patents Search

• Indian Patent 247630 “Oxirane macroporous beads for enzyme immobilization and process there of” granted on 28.4.2011. Find it on All India Patents

• Indian patent 253959 “Process for the synthesis of semi-synthetic penicillin or cephalosporin antibiotic using Penicillin G Acylase biocatalyst from Achromobacter sp CCM 4824 expressed in E.coli BL21 CCM 7394”, granted on 6.9.2012. Find it on All India Patents

• US patent 8389551B2 “Optical enantiomers of Phenyramidol and process for chiral synthesis” granted on 5.3.2013. Find it on Google Patents Search

Latest Publications

• “Immobilization and characterization of recombinant Candida antarctica lipase B on poly(glycidyl methacrylate-ter-divinyl benzene-ter-ethylene dimethacrylate) beads, “DILBEADS^TM TA ”, published in Biocatalysis and Biotransformation, 7.2.2013

• Penicillin G acylase from Achromobacter sp. CCM 4824 - "An efficient biocatalyst for syntheses of beta-lactam antibiotics under conditions employed in large-scale processes”, published in Applied Microbiology Biotechnology, 15.5.2013.

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